TRANSLATIONAL NEUROENGINEERING is a vibrant area of biomedical research, technology development, and clinical translation. Our goal is to pursue basic and clinically motivated neuroscience research, develop innovative neurotechnologies, and translate them for clinical applications and for industrial uses and dissemination. Our research goes from bench to bedside. Our faculty and laboratories are equally interested in basic research and innovation/entrepreneurship.
Neurotechnologies for Prosthesis and Brain Machine Interface
NEUROTECHNOLOGIES. Development of advanced neurotechnologies, including micro/nanosensors for neural interface, neural interface circuits and devices, fully implantable neural interfaces and prosthesis.
NEURAL INTERFACES. Innovative technologies and platforms for interfacing to the nervous system: including microfluidic chips, micro and nanosensors, and interfaces to neurons in vitro, in vivo and for eventual clinical implants. Interfaces to peripheral and visceral nervous system.
NEUROPROSTHESIS. Combining algorithms and implantable devices to build neuroprosthesis for motor and sensory function restoration after injury to the nervous system (peripheral, spinal and cortex). The goal is to develop bidirectional interfaces (sensory input, motor output).
BRAIN MACHINE INTERFACE. Computational algorithms for interpreting brain signals (spikes from neurons, EEG, ECoG) and utilizing these algorithms for building brain machine interfaces for motor, sensory, and speech decoding.
LOCOMOTION. Modeling the motor system through neuronal and spinal models, implementing these in silicon, and testing the device in locomotion systems (animal models and robotics)
VISION. Design of active pixel imagers and cameras inspired by the visual system. Applications include endoscope, retinal prosthesis and even drones.
TOUCH. Prosthetic hands do not have sensory perception. Tactile sensors mimicking receptors in the skin convey sensor of touch, temperature, and pain in a biomimetic way.
NEUROPHOTONICS. Novel imaging system that involves design of optical interface and imaging (e.g. laser speckle interference, optical coherence tomography, fluorescence imaging) of brain in chronic, awake, behaving animals.
FUNCTIONAL BRAIN IMAGING. Brain imaging with high resolution MRI as well as other contrast modalities provide the highest resolution images of vasculature in the brain, allowing studies of brain tumor progression and treatment.
EPILEPSY MONITORING AND TREATMENT. Solutions to monitoring and interpreting epileptic brain rhythms, recorded as EEG and ECoG signals, and developing predictive methods for treatment.
CHRONIC PAIN AND SPINAL CORD STIMULATION. Integrating state-of-the-art electrophysiological experiments with computational models of pain system to design new therapies for chronic pain.
SPINAL CORD INJURY AND RESTORATION. Electrophysiological investigations, and novel therapies including hypothermia, stem cell, and neurotrophic factors for spinal cord repair and regeneration to achieve translation.